Bone & Cartilage: From Development to Human Diseases

Suzhou, China 
October 24-28, 2016

Abstract Deadline: September 11, 2016

Conference Agenda

Organized by:

Hongwei Ouyang, Zhejiang University, China

Thomas Pap, University Münster, Germany

Sakae Tanaka, The University of Tokyo, Japan

Yingzi Yang, Harvard University, USA

We are pleased to announce Cold Spring Harbor Asia conference on Bone & Cartilage: From Development to Human Diseases which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. The conference will begin at 7:00pm on the evening of Monday October 24, and will conclude after lunch on October 28, 2016.

The conference will include eight oral sessions and one poster session covering the latest findings across many topics in bone and cartilage. Many talks will be selected from the openly submitted abstracts on the basis of scientific merit and relevance. Social events throughout the conference provide ample opportunity for informal interactions.

Major Topics:
1. New Horizon of Bone Cell Biology
2. Osteoarthritis and Cartilage Biology
3. Chondrocyte Homoestasis in Health, Disease and Regeneration
4. Bone Biology and Diseases
5. Signaling Mechanisms in Cartilage
6. Skeletal Development
7. Craniofacial Bone Development
8. Skeletal Stem Cells

Keynote Speakers:
Yan Jin, Fourth Military Medical University, CHINA
Abstract title: Dysfunction of MSCs affected by inflammatory microenvironment during bone aging
Bjorn Olsen, Harvard Medical School, USA

Invited Speakers:
Nunzio Bottini,University of California San Diego, USA
Abstract title: Regulation of rheumatoid synoviocyte invasiveness by the proteoglycan switch
Xu Cao, Johns Hopkins Univeristy, School of Medicine, USA
Abstract title: Mesenchymal Stem Cells in Bone Remodeling and Osteoarthritis
Danny Chan, University of Hong Kong, Hong Kong
Abstract title: Activating endoplasmic reticulum stress in osteocytes results in hyperostosis consistent with craniodiaphyseal dysplasia
Kathryn Cheah, The University of Hong Kong, Hong Kong
Abstract title: Mechanisms of hypertrophic chondrocyte adaptation and survival under ER stress
Di Chen, Rush University, USA
Abstract title: Wnt Signaling and Diffuse Idiopathic Skeletal Hyperostosis (DISH)
Francesco Dell'Accio, William Harvey Research Institute, UNITED KINGDOM
Abstract title: Agrin, a signalling proteoglycan suporting cartilage homeostasis
Xizhi Guo, Shanghai Jiao Tong University, CHINA

Wei Hsu, University of Rochester, USA
Mohit Kapoor, University Health Network, CANADA
Abstract title: Identification of microRNAs-181a-5p and microRNA-4454 as mediators of facet cartilage degeneration
Dae-Won Kim, Yonsei University, SOUTH KOREA
Abstract title: Chondrocyte hypertrophy control during endochondral ossification
Ophir Klein, University of California, San Francisico, USA
Abstract title: Continuously-growing teeth as a model for mineralized tissue renewal
Kingston King-lun Mak, The Chinese University of Hong Kong, HONG KONG
Abstract title: Hedgehog Signaling in Bone Regulates Whole Body Energy Metabolism Through a Bone-Adipose Endocrine Relay Mediated by PTHrP and Adiponectin
Hongwei Ouyang, Zhejiang University, School of Medicine, CHINA
Thomas Pap, University Münster, GERMANY
Abstract title: The role of fibroblast-like synoviocytes in cartilage destruction and disease progression in rheumatoid arthritis.
Taku Saito, The University of Tokyo, JAPAN
Abstract title: Regulation of Articular Cartilage Homeostasis and Osteoarthritis Development by the NF-kappaB signaling
Natalie Sims, ST Vincent's Institute/ The University of Melbourne, AUSTRALIA
Abstract title: Sex-dependent control of cortical bone formation (corticalization) depends on cytokine signalling in osteocytes
Sakae Tanaka, The University of Tokyo, JAPAN
Abstract title: Genome-wide mapping of promoter and enhancer elements for RANKL-induced osteoclastogenesis
Cun-Yu Wang, University of California, Los Angeles, USA
Abstract title: Wnt 4 Prevents Bone Loss by Inhibiting NF-kB
James Whiteford, Barts and the London School of Medicine and Dentis, UNITED KINGDOM
Abstract title: Targeting angiogenesis for the treatment of RA.
Yingzi Yang, Harvard University, USA
Abstract title: Gas Signaling In Development And Diseases
Hu Zhao, Texas A&M University, USA
Abstract title: In vivo identification and regulating niche of mesenchymal stem cells.
Weiguo Zou, Shanghai Institutes for Biological Sciences, CAS, CHINA
Abstract title: The E3 ligase SMURF2 regulates bone homeostasis by disrupting VDR/SMAD3 interaction in osteoblasts

We encourage abstracts to contain new and unpublished materials. The abstracts must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentation will be made by the organizers. Status (fellow's talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers. 

We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. A certain number of presentations by graduate students and postdocs in this conference will be selected as fellowship (USD $100-$500) awards. For more details, please visit Stipends

We look forward to seeing you at Suzhou in October, 2016.

Sponsored by:


Package Content:

Package Type

Early Registration

Late Registration

Payment Deadline:

September 26, 2016

Payment Deadline:

Before Arrival





















Please kindly note:

1. Registration includes food, but does NOT include Housing. Due to requests from participants to provide more housing at lower prices, we have expanded our housing options to include some lower priced nearby hotels. After completing the online registration, you will receive a link to the full list of housing options.
*Reference Room Rate:
CNY 500 per standard room per night in the Conference Hotel (Worldhotel Grand Dushulake Suzhou)
Up from CNY 200 per standard room per night in nearby budget hotels (within 5 km)
CNY 400-700 per standard room per night in nearby 4-5 star hotels

2. The meeting registration is an integral package. We encourage all our participants to stay for the full meeting period and communicate with each other. No refund/discount or day pass is available for partial participation.

3. The early price will be available if the full payment is finished before the exact due date.
For USD participants, we will automatically change your package price to the update one if we could not successfully charge the payment from your registered credit card before the deadline.
For CNY participants, we will automatically change your package price to the update one if our bank account could not receive your full payment by wire transfer before the deadline.

4. For late registrations, your registration materials may not be guaranteed since the order is usually made in advance.

5. Please inform us your special request on food (vegetarian, kosher…etc.) or other things during the online registration or email us as early as possible so that we could make relevant arrangement accordingly.

6. Student package is exclusively designed for all the graduate, undergraduate and doctor students who have not received the doctor degree. (Student ID will be required upon arrival).

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