Liver Diseases and Tumorigenesis: from Bench to Bedside

Suzhou, China
April 25-29, 2016

Abstract deadline:March 13th, 2016

Organized by:

Gen-Sheng Feng, University of California San Diego, USA

Hongyang Wang, Eastern Hepatobiliary Surgery Hospital/Institute, China

Jessica Zucman-Rossi, INSERM, France

We are pleased to announce the Cold Spring Harbor Asia conference on Liver Diseases and Tumorigenesis: from Bench to Bedside which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. The conference will begin at 7:00pm on the evening of Monday April 25, and will conclude after lunch on Friday April 29, 2016.

The conference will include eight oral sessions and one poster session covering the latest findings across many topics in liver research. Many talks will be selected from the openly submitted abstracts on the basis of scientific merit and relevance. Social events throughout the conference provide ample opportunity for informal interactions.

The conference will cover the latest and most important advancement in our understanding of liver development, metabolism, disorders and cancer, from basic, translational and clinical studies. Attentions will be paid on viral hepatitis, alcoholic and non-alcoholic fatty liver diseases. In particular, liver cancer is now escalated to be the 2nd cause of cancer mortality, the talks will cover a broad range of topics, including genomics, epigenetics, signaling, immunotherapy and large-scale clinical data analysis. Many talks will be selected from submitted abstracts on the basis of scientific merit and relevance. Young scientists, physicians and pathologists are particularly encouraged to attend the conference and join the social events throughout the meeting for informal scientific interactions.

Major Topics:
1. Liver progenitor cells and tumor-initiating cells
2. Liver injuries, fibrosis and cirrhosis
3. Alcoholic and non-alcoholic fatty liver diseases
4. Translational and clinical studies of liver cancer
5. Genomics and bioinformatics of liver diseases
6. Liver metabolism and metabolic disorders
7. Hepatic inflammation and immunity

Keynote Speakers:
Scott Lowe , Memorial Sloan Kettering Cancer Center/HHMI , USA
Abstract title: Tumor Suppressor & Tumor Maintenance Genes

Invited Speakers:
David Brenner , University of California, San Diego , USA
Abstract title: Genetics of liver fibrosis
David Cohen , Brigham and Women's Hospital , USA
Abstract title: Acyl-CoA Thioesterase-Mediated Metabolic Regulation
Sabine Colnot , Institut Cochin, INSERM U1016 , FRANCE
Abstract title: Metabolic Reprogramming in Beta-Catemin-Driven Liver Carcinogenesis in Mice
Chantal Desdouets , INSERM U567 , FRANCE
Abstract title: Liver polyploidy: Dr Jekyll or Mr Hide?
Gen-Sheng Feng , University of California, San Diego , USA
Abstract title: Cooperating or opposing roles of Pten and Shp2 in hepatocarcinogenesis or leukemogenesis
Eithan Galun , Hadassah Hebrew University Hospital , ISRAEL
Abstract title: Mir 122 is a hepatic-hormone with systemic effects
Ping Gao, University of Science & Techonology of China, CHINA
Abstract title: The regulation of metabolic reprogramming in hepatocellular carcinoma cells
Mathias Heikenwälder , Technische Universitat Munchen , GERMANY
Abstract title: Identification of novel targets to treat NASH and its transition to HCC
Lijian Hui, Institute of Biochemistry and Cell Biology, SIBS, CAS, CHINA
Abstract title: Direct Reprogramming of Human Fibroblasts to Functional Hepatocyte-Like Cells
Sophie Lotersztajn , Center for Research on Inflammation, Inserm, France
Abstract title: Immunoregulation of liver fibrosis: novel pathways
Shelly Lu , Cedars-Sinai Medical Center , USA
Abstract title: Role of Methionine Adenosyltransferase 1A in Liver Cancer

Xuemei Lu, Beijing Institute of Genomics, CHINA
Abstract title: Evolution of cancer cell populations
Tom Lüdde 
, University Hospital RWTH Aachen , GERMANY
Abstract title: Programmed cell death pathways in liver injury and hepatocarcinogenesis
Atsushi Miyajima , University of Tokyo , JAPAN
Abstract title: Remodeling of the biliary tree during liver regeneration
Kanaga Sabapathy, National Cancer Centre Singapore, SINGAPORE
Abstract title: A Bifunctional Role for C-JUN in Regulating Liver Homeostasis during Fibrosis
Robert Schwabe , Columbia University , USA
Abstract title: Contribution of hepatic stellate cells to hepatocarcinogenesis
Young-Joon Surh, Seoul National University, SOUTH KOREA
Abstract title: Mutation and subsequent activation of Nrf2 in diethylnitrosamine-treated mouse liver accelerates progression of hepatocellular carcinoma through metabolic alterations
Hongyang Wang , Eastern Hepatobiliary Hospital/Institute of Shanghai , CHINA
Abstract title: New insights into inflammation regulation and Liver Cancer
Xiao-Fan Wang , Duke University School of Medicine , USA
Abstract title: Inflammation-dependent IL-18 signaling restricts hepatocellular carcinoma growth by systematic modulation of lymphocyte activity
Xin Wei Wang , National Institute of Health , USA
Abstract title: Integrated Omics Investigation of Tumor Heterogeneity and Drivers in Liver Cancer
Holger Willenbring , University of California San Francisco , USA
Abstract title: Hepatocyte plasticity in liver regeneration and cancer
Lars Zender , University Hospital Tuebingen , Germany
Abstract title: Direct in vivo shRNA screening for functional target discovery in hepatocellular carcinoma
Jessica Zucman-Rossi , INSERM U674 , FRANCE
Abstract title: Revisiting nosology of liver tumors through the scope of genomics

We encourage abstracts to contain new and unpublished materials. The abstracts must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentation will be made by the organizers. Status (fellow's talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers. 

We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. A certain number of presentations by graduate students and postdocs in this conference will be selected as fellowship (USD $100-$500) awards. For more details, please visit Stipends

We look forward to seeing you at Suzhou in April, 2016.

Sponsored by:


Package Content:

Package Type

Early Registration

Late Registration

Payment Deadline:

March 28, 2016

Payment Deadline:

Before Arrival





















Please kindly note:

1. Registration includes food, but does NOT include Housing. Due to requests from participants to provide more housing at lower prices, we have expanded our housing options to include some lower priced nearby hotels. After completing the online registration, you will receive a link to the full list of housing options.
*Reference Room Rate:
CNY 500 per standard room per night in the Conference Hotel (Worldhotel Grand Dushulake Suzhou)
Up from CNY 200 per standard room per night in nearby budget hotels (within 5 km)
CNY 400-700 per standard room per night in nearby 4-5 star hotels

2. The meeting registration is an integral package. We encourage all our participants to stay for the full meeting period and communicate with each other. No refund/discount or day pass is available for partial participation.

3. The early price will be available if the full payment is finished before the exact due date.
For USD participants, we will automatically change your package price to the update one if we could not successfully charge the payment from your registered credit card before the deadline.
For CNY participants, we will automatically change your package price to the update one if our bank account could not receive your full payment by wire transfer before the deadline.

4. For late registrations, your registration materials may not be guaranteed since the order is usually made in advance.

5. Please inform us your special request on food (vegetarian, kosher…etc.) or other things during the online registration or email us as early as possible so that we could make relevant arrangement accordingly.

6. Student package is exclusively designed for all the graduate, undergraduate and doctor students who have not received the doctor degree. (Student ID will be required upon arrival).

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