Yeast and Life Sciences 

Suzhou, CHINA

June 21-24, 2021

Abstract deadline: May 14, 2021

Organized by:


Daochun Kong, Peking University

Hisao Masai, Tokyo Metropolitan Institute of Medical Science

Frank Uhlmann, The Francis Crick Institute

Marco Foiani, The FIRC Institute of Molecular Oncology

Brenda J. Andrews, University of Toronto

We are pleased to announce the Cold Spring Harbor Asia conference on Yeast and Life Sciences which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. The conference will begin at 7:00pm on the evening of Monday June 21, and will conclude after lunch on Thursday June 24, 2021.

The conference will include six oral sessions and one poster session covering the latest findings across many topics in
Yeast. While domestic participants within China will attend the meeting in-person, Overseas participants who cannot attend the meeting physically will be able to join the meeting LIVE via Zoom.  Many talks will be selected from the openly submitted abstracts on the basis of scientific merit and relevance. Social events throughout the conference provide ample opportunity for informal interactions.

Major Topics:

1. Cell Growth Controls

2. Organelles

3. Cellular Metabolism

4. Chromosome

5. DNA Replication, Recombination and Repair 

Keynote Speakers:

Nancy Kleckner, Harvard University

Abstract title: Seeing chromosomes in budding yeast (and other organisms)

Bruce Stillman, Cold Spring Harbor Laboratory

Abstract title: Mechanism, regulation and evolution of DNA replication origin specification in eukaryotic cells


Invited Speakers:

Andres Aguilera, Universidad de Sevilla-CSIC

Abstract title: Cell cycle-specific mechanisms for harmful R-loop prevention in yeast

Brenda Andrews, University of Toronto

Abstract title: From phenotypes to pathways: global analysis of cellular networks using systematic yeast genetics and single cell image analysis

Dana Branzei, IFOM, FIRC Institute of Molecular Oncology

Abstract title: Mus81-Mms4 endonuclease is turned over by Esc2-STUbL-Cullin8 in mitosis to maintain genome integrity

Jürg Bähler, University College London

Abstract title: A pyruvate kinase variant of fission yeast affects energy metabolism, cell regulation, growth and stress resistance

Orna Cohen-Fix, NIH, NIDDK

Abstract title: Nuclear size regulation in budding yeast

Li-lin Du, National Institute of Biological Sciences, Beijing

Abstract title: Selective autophagy in fission yeast

Marco Foiani, IFOM The FIRC Institute of Molecular Oncology

Abstract title: DNA damage response and repair efficiency rely on metabolic tuning of amino acid uptake, AMPK and Torc1 networks, and PP2A activity.

Shiv Grewal, National Cancer Institute, National Institutes of Health

Abstract title: Methylated histones transmit epigenetic memory: lessons from fission yeast 

Xiangwei He, Zhejiang University

Abstract title: Rapid & reversable mutations generate subclonal genetic diversity

Alan Hinnebusch, NIH

Abstract title: “Downstream activation sequences” and feedback loops of chromatin remodeling complexes regulate binding and transcriptional stimulation by Gcn4

Takehiko Kobayashi, University of Tokyo

Abstract title: DNA replication initiation affects stability of ribosomal RNA gene repeat and lifespan

Daochun Kong, Peking University

Abstract title: Initiation of Chromosomal DNA Replication in Eukaryotes

Qing Li, Peking University

Abstract title: Dissecting the replisome-histone chaperones guided nucleosome assembly network

Mart Loog, University of Tartu

Abstract title: Temporal control of cell cycle via multi-site phosphorylation in S.cerevisiae

Huiqiang Lou, China Agricultural University

Abstract title: Metabolic remodeling maintains a reducing environment for rapid activation of the DNA replication checkpoint

Sophie Martin, University of Lausanne

Abstract title: Cell patterning by secretion-induced membrane flows, and other membrane events

Richard Maraia, National Institute of Child Health and Human Development, National Institutes of Health

Abstract title: tRNA synthesis by RNA polymerase III: Considering attributes involved in Pol III nuclear and cytoplasmic transcription functions

Hisao Masai, Tokyo Metropolitan Institute of Medical Science

Abstract title: Roles of G4 binding and multimization of Rif1 in S phase regulation in fission yeast cells

Sahand Jamal Rahi, École polytechnique fédérale de Lausanne (EPFL)

Abstract title: Single-cell analysis reveals quantitative patterns of DNA damage checkpoint adaptation

Frederick Roth, University of Toronto and Mount Sinai Hospital

Abstract title: Using yeast for large-scale testing of functional human sequence variation

Maya Schuldiner, Weizmann Institute of Science

Abstract title: Systematic analysis of contact site proteomes reveals novel players in cellular homeostasis

Lars Steinmetz, EMBL

Abstract title: Learning from synthetic genomic applications in yeast

Tomoyuki Tanaka, University of Dundee

Abstract title: Aurora B–INCENP localization at centromeres/inner kinetochores is essential for chromosome bi-orientation in budding yeast

Yuichi Taniguchi, Kyoto University

Abstract title: Nucleosome-level 3D organization of the yeast genome

Genevieve Thon, University of Copenhagen

Abstract title: Roles of replication factors in heterochromatin formation, in fission yeast

Michael Tyers, University of Montréal

Abstract title: TBA

Frank Uhlmann, The Francis Crick Institute

Abstract title: From DNA to Chromosomes – the Structure and Function of SMC Complexes

Elçin Unal, University of California at Berkeley

Abstract title: TBA

Dan Zhang, Temasek Life Science Laboratory

Abstract title: ER-PM contacts: formation, function and regulation

Liangran Zhang, Shandong University

Abstract title: Pds5 regulates chromosome axis length and recombination frequency in meiosis

Xiaolan Zhao, Memorial Sloan Kettering Cancer Center

Abstract title: Yeast leads the way: insights into the functions and structures of the Smc5/6 complex

Jin-Qiu Zhou, Institute of Biochemistry and Cell Biology, CAS

Abstract title: Construction and characterization of single-chromosome fission yeast strains reveal the configuration robustness of a functional genome

We encourage abstracts to contain new and unpublished materials. The abstracts must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentation will be made by the organizers. Status (fellow's talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers. 

We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. A certain number of presentations by graduate students and postdocs in this conference will be selected as fellowship (USD $100-$500) awards. For more details, please visit  

We look forward to seeing you at Suzhou in June, 2021.


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