We are pleased to announce the Cold Spring Harbor Asia conference on Optical Interrogation of Neural Structure and Dynamics Underlying Behavior will be held in Awaji, Japan, located approximately 60 km west of Osaka city.

The conference will begin in the evening of Tuesday November 11, 2025, and will conclude after lunch on November 14, 2025. The conference will include eight oral sessions and one poster session covering the latest findings across many topics in Immunology, particularly concerning immunoreceptor, signaling pathways as well as immunotherapy. Many talks will be selected from the openly submitted abstracts on the basis of scientific merit and relevance. Posters will be up for viewing and discussion throughout the conference. Social events throughout the conference provide ample opportunity for informal interactions. 

Conference Venue & Accommodation
Cold Spring Harbor Asia conferences in JAPAN are arranged in Awaji Yumebutai International Conference Center (https://www.yumebutai.co.jp/lang/en.html), which is part of a one-of-a-kind “environment creation” project equipped with professional conference facilities and blended into the magnificent landscape, designed by the famous architect Tadao Ando. Meeting participants are strongly recommended to stay at the conference hotel, Grand Nikko Awaji (https://www.okura-nikko.com/japan/awaji/grand-nikko-awaji/) during the meeting with the rest of the participants if possible. The accommondation booking URL will be sent to you after completion of meeting registration.

Major Topics:

1. Antigen receptors

2. Co-stimulatory and co-inhibitory receptors

3. Modulation of immunoreceptors by other receptor signaling pathways

4. Immune checkpoint blockade therapy 

5. Immune cell therapy

Keynote Speakers:

Crystal Mackall, Stanford University

Shimon Sakaguchi, Osaka University

Invited Speakers: 

Yvonne Chen, University of California, Los Angeles

Marco Colonna, Washington University in St. Louis

Michael Dustin, University of Oxford

Naoki Hosen, Osaka University

Enfu Hui, University of California, San Diego

Morgan Huse, Memorial Sloan Kettering Cancer Center (MSKCC)

Alice Kamphorst, Icahn School of Medicine at Mount Sinai

Kyung-Mi Lee, Korea University

Qijing Li, Agency for Science, Technology and Research (A*STAR)

Susana Minguet, University of Freiburg

Daniel Mucida, The Rockefeller University

Pamela Ohashi, University Health Network

Taku Okazaki, The University of Tokyo

Jamie Rossjohn, Monash university

Wolfgang Schamel, University of Freiburg

Andre Veillette, Institut de Recherches Cliniques de Montreal

Haopeng Wang, ShanghaiTech University

Chenqi Xu, Shanghai Institute of Biochemistry and Cell Biology, CAS

Huji Xu, Shanghai Changzheng Hospital

Sho Yamasaki, Osaka University

Christina Zielinski, Leibniz Institute for Natural Product Research & Infection Biology

And more...

We encourage abstracts to contain new and unpublished materials. The abstracts must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentation will be made by the organizers. Status (fellow's talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers. 

Fellowship: 
We are eager to have as many young people as possible to attend our international meetings since they are likely to benefit most from meeting other international colleagues in the same field. A certain number of presentations by graduate students and postdocs in this conference will be selected as fellowship (USD $100-$500) awards after the meeting to off set the registration fee. Announcements of the awardees will be made during the Banquet of the meeting.

We look forward to seeing you at Awaji, Japan in November, 2025.