Disease Modeling and Drug Discovery
Suzhou, China
August 25-29, 2014
Abstract Deadline extended to: July 6, 2014

Schedule Overview

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Organized by:

Yanhong Shi, Beckman Research Institute of City of Hope, USA
Michael Yaffe, California Institute for Regenerative Medicine, USA
Duanqin Pei, Guangzhou Institute of Biomedicine and Health, China
Toru Takumi, RIKEN Brain Science Institute, Japan

Scientific Advisor:
Shinya Yamanaka, Kyoto University, Japan
Gang Pei, Shanghai Institutes of Academy of Sciences, China

We are pleased to announce Cold Spring Harbor Asia conference on Disease Modeling and Drug Discovery which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. The conference will begin at 7:00pm on the evening of Monday August 25, and will conclude after lunch on August 29, 2014.

The conference will include eight oral sessions and one poster session covering the latest findings across many topics in disease modeling and drug discovery. Many talks will be selected from the openly submitted abstracts on the basis of scientific merit and relevance. Social events throughout the conference provide ample opportunity for informal interactions.

Recent developments in stem cell biology and cellular reprogramming have catalyzed unprecedented advances in disease modeling and drug discovery. The ability to derive distinct human cell types is enabling innovative approaches to create in vitro disease models and to develop new strategies for the identification and testing of novel therapeutics. The meeting will provide an opportunity to share new ideas and information about the generation of induced pluripotent stem cells (iPSCs), reprogramming in human oocytes using somatic cell nuclear transfer (SCNT), the derivation and analysis of diverse human cell types, and the development of disease-in-a-dish models as well as animal models. Additionally, there will be much focus on the use of these models for understanding disease mechanisms and discovering novel drugs for treating injury and diseases. Studies focused on neurodegenerative diseases, neurological and psychiatric disorders, cardiac diseases, diabetes and aging-related disorders will be among the highlighted topics for discussion. Leading scientists from around the globe will participate in discussions and provide penetrating insights towards a deeper understanding of human diseases and rationales for the development of more effective drugs and therapeutic solutions.

Cardiac disease modeling and drug discovery
Modeling psychiatric disorders using animal models
Modeling neurodevelopmental diseases using iPSCs
Dissecting neurodegenerative diseases using stem cells
Drug discovery using disease models
Cellular reprogramming
Clinical applications of disease models
Translating discovery to the clinics

Keynote Speakers:
Lorenz Studer, Sloan-Kettering Institute for Cancer Research, USA
Abstract title:TBA
Roberto Iacone, Hoffman-La Roche Ltd, Switzerland, SWITZERLAND

Abstract title:Disease modeling and phenotypic drug screening for diabetic cardiomyopathy using human inducible pluripotent stem cells

Invited Speakers:
Anne G. Bang, Sanford-Burnham Medical Research Institute, USA
Abstract title:Human Induced Pluripotent Stem Cells and Patient Specific Cell-Based Disease Models for Drug Discovery

Thomas Bourgeron, Institut Pasteur, FRANCE
Abstract title:Genes, Synapses and Autisms
Arlene Chiu, Beckman Research Institute of City of Hope, USA
Abstract title: The Rocky Road from Discovery to Treatment
Ing-Ming Chiu, National Health Research Institutes, Taiwan, TAIWAN
Abstract title: Neural Stem Cells and Induced Neurons in Peripheral Nerve Injury Repair
Alan Colman, Harvard University / Institute of Medical Biology, Singapore
Abstract title: The X Factor: Dynamics of X Chromosome Expression during and after Reprogramming of Human Somatic Cells
Dieter Egli, The New York Stem Cell Foundation Research Institute, USA
Abstract title:Reprogramming in Human Ooyctes
Yadong Huang, University of California San Francisco, Gladstone Institute, USA
Abstract title: Modeling Neurodegenerative Diseases and Drug Screening Using Human iPSCs
Haruhisa Inoue, Kyoto University, JAPAN
Abstract title:The Use of iPSCs toward the Treatment of Neurodegenerative Diseases
Dong-Wook Kim, Yonsei University College of Medicine, Korea
Abstract title: Modeling and Drug Discovery of X-linked Adrenoleukodystrophy using iPS Cells
Eric Klann, New York University, USA
Abstract title: Translating Translational Control in Brain Disorders
Guo-Li Ming, Johns Hopkins University, USA
Abstract title: Modeling Complex Psychiatric Disorders Using iPSCs
Stephen Minger, GE Healthcare, UK
Abstract title: Innovating Preclinical Drug Discovery and Human Cell Therapy
Duanqing Pei, Chinese Academy of Sciences, CHINA
Abstract title:TBA
Bruno Reversade, Institute of Medical Biology, A*STAR, SINGAPORE
Abstract title: Age-defying Proline, Because You Are Worth It
Yanhong Shi, Beckman Research Institute of City of Hope, USA
Abstract title: Modeling Neurological Diseases using Patient iPSCs
Toru Takumi, RIKEN Brain Science Institute, JAPAN
Abstract title: CNV Models for Autism Spectrum Disorders
Leslie Thompson, University of California Irvine, USA
Abstract title:Discovery and validation of therapeutic targets for Huntington's disease using HD iPS cells
Joseph Wu, Standford University, USA
Abstract title: Cardiac Stem Cells for Modeling Heart Disease and for Drug Discovery
Michael Yaffe, California Institute for Regenerative Medicine, USA
Abstract title:Large-scale Derivation and Banking of iPSCs for Complex Human Diseases

We encourage abstracts to contain new and unpublished materials. The abstracts must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentation will be made by the organizers. Status (fellow's talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers.

We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. A certain number of presentations by graduate students and postdocs in this conference will be selected as fellowship (USD $200-$500) awards. For more details, please visit Stipends

We look forward to seeing you at Suzhou in June 2014.

Package Content:

Package Type

Early Registration

Late Registration

Payment Deadline:

July 28, 2014

Payment Deadline:

Before Arrival





















Please kindly note:

1. Registration includes food, but does NOT include Housing. Due to requests from participants to provide more housing at lower prices, we have expanded our housing options to include some lower priced nearby hotels. After completing the online registration, you will receive a link to the full list of housing options.
*Reference Room Rate:
CNY 500 per standard room per night in the Conference Hotel (Worldhotel Grand Dushulake Suzhou)
Up from CNY 200 per standard room per night in nearby budget hotels (within 5 km)
CNY 400-700 per standard room per night in nearby 4-5 star hotels

2. The early price will be available if the full payment is finished before the exact due date.
For USD participants, we will automatically change your package price to the update one if we could not successfully charge the payment from your registered credit card before the deadline.
For CNY participants, we will automatically change your package price to the update one if our bank account could not receive your full payment by wire transfer before the deadline.

3. For late registrations, your registration materials may not be guaranteed since the order is usually made in advance.

4. Please inform us your special request on food (vegetarian, kosher…etc.) or other things during the online registration or email us as early as possible so that we could make relevant arrangement accordingly.

5. Student package is exclusively designed for all the graduate, undergraduate and doctor students who have not received the doctor degree. (Student ID will be required upon arrival).

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