Targeting Cell Death Mechanisms for the Treatment of Human Diseases

Suzhou, China 
November 9-13, 2015  

Abstract Deadline: September 18, 2015

Organized by:

Junying Yuan, Harvard Medical School, USA
Jiahuai Han, Xiamen University, CHINA
Douglas Green, St. Jude's Children's Hospital, USA
Domagoj Vucic, Genentech, USA


We are pleased to announce the Cold Spring Harbor Asia conference on Targeting Cell Death Mechanisms for the Treatment of Human Diseases which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. The conference will begin at 7:00pm on the evening of Monday November 9, and will conclude after lunch on November 13, 2015.

The conference will include eight oral sessions and one poster session covering the latest findings across many topics in cell death research. Many talks will be selected from the openly submitted abstracts on the basis of scientific merit and relevance. Social events throughout the conference provide ample opportunity for informal interactions.

With the generous support from GSK and to promote the education value of the CSHA, we will provide GSK award to reduce the registration fee of each student for 1000RMB, including both domestic Chinese students and international students. Please note that this one-time-only policy will be offered as "first come, first serve" basis until the fund from GSK is exhausted. Applicants should indicate their interest by sending an e-mail to Connie Zhang ([email protected]). Confirmation of interest will be confirmed by e-mail. We will try to let you know the selection results as soon as possible by email.

Major Topics:
1. Targeting tumor survival mechanisms;
2. Targeting autophagy;
3. Targeting necroptosis;
4. Targeting mitochondria;
5. Targeting apoptosis;
6. Targeting innate immunity.

Keynote Speakers:
Lewis Cantley, Cornell University, USA
Abstract title:Phosphoinositide 3-Kinase and cancer metabolism

Invited Speakers:
John Bertin, GlaxoSmithKline, USA
Abstract title:RIPK1 therapeutics: from concept to clinic
Alexei Degterev, Tufts University, USA
Abstract title:RIPK1 and RIPK3 – new players in the regulation of acute inflammation.
Douglas Green, St. Jude Children's Research Hospital, USA
Abstract title:Death and un-death in necroptosis
Jiahuai Han, Xiamen University, CHINA
Abstract title:A role of necroptosis in caecum-related inflammatory disease
Sudan He, Soochow University, CHINA
Abstract title:Programmed necrosis in host defense against viral infection
Yongkeun Jung, Seoul National University, KOREA
Abstract title: Implication of FcgammaRIIb and its associated mediator in amyloid-beta neurotoxicity and Alzheimer’s disease
William Kaiser, Emory University School of Medicine, USA
Abstract title:Viral modulation of extrinsic cell death pathways
Michelle Kelliher, University of Massachusetts Medical School, USA
Abstract title: RIPK1 expression in dendritic cells maintains immune homeostasis
Guido Kroemer, INSERM, FRANCE
Abstract title:Chemotherapy-induced anticancer immunosurveillance: The involvement of pathogen recognition receptors
Zheng-Gang Liu, NIH / NCI, USA
Abstract title:Understanding the regulation of TNF-induced necroptosis
Andreas Linkermann, Georges-Köhler-Haus for Biomedical Research and Transplantation, GERMANY
Abstract title:human relevance of MLKL-mediated necroptosis
Jean-Claude Martinou, Université de Genève, SWITZERLAND
Abstract title:The mitochondrial pyruvate carrier: regulation of its activity in the metabolism of cancer cells and neurons
Shige Nagata, Osaka University, JAPAN
Abstract title: Exposure of phosphatidylserine during apoptosis and engulfment of dead cells
Manolis Pasparakis, University of Cologne, GERMANY
Serge Przedborski, Columbia University Medical Center, USA
Abstract title:Does Necroptosis Drive the Degeneration of Motor Neurons in Amyotrophic Lateral Sclerosis?
David Rubinsztein, University of Cambridge, UK
Abstract title:Targetting aggregate-prone protein accumulation in neurodegenerative diseases
Feng Shao, National Institute of Biological Sciences, CHINA
Abstract title: Pyroptosis in anti-bacterial immunity: sensing and execution
Yufang Shi, Institute of Health Sciences, CHINA
Abstract title:Mesenchymal Stem Cells and Tumor Progression
Andreas Strasser, Walter & Eliza Hall Institute of Medical Rsch., AUSTRALIA
Abstract title:Identification of the critical p53 tumor suppression mechanisms in vivo
Liming Sun, Institute of Biochemistry and Cell Biology, CAS, CHINA
Abstract title:MLKL navigates the TNF signaling from membrane back to membrane
Qiang Sun, Institute of Biotechnology, CHINA
Abstract title:Cannibalism by entosis: Competition for malignancy
Peter Vandenabeele, Ghent University, VIB, BELGIUM
Abstract title:Targeting regulated necrosis in cancer
Domagoj Vucic, Genentech, Inc, USA
Abstract title:Regulation of inflammatory cell death signaling by RIP1 modifications
Xiaochen Wang, National Institute of Biological Sciences, CHINA
Abstract title: To eat correctly:Phospholipid signaling in apoptotic cell recognition and internalization
Xiaodong Wang, National Institute of Biological Sciences, CHINA
Eileen White, Rutgers University/The Cancer Institute of New Jersey, USA
Abstract title:Autophagy, Metabolism and Cancer
Hong Wu, UCLA School of Medicine, USA
Chonglin Yang, Institute of Genetics and Developmental Biology, CHINA
Abstract title: Mechanisms of mTOR-independent biogenesis of lysosomes
Richard Youle, National Institutes of Health, USA
Abstract title:Damage Control and Parkinson's Disease: Roles of the kinase PINK1 and the ubiquitin ligase Parkin in the autophagy of mitochondria in vitro and in vivo
Li Yu, Tsinghua University, CHINA
Abstract title: The regulation of energy deprivation induced autophagy
Junying Yuan, Harvard Medical School, USA
Haibing Zhang, Institute for Nutritional Sciences, CHINA
Abstract title:MLKL regulate necroptosis and NLRP3 inflammasome
Boris Zhivotovsky, Karolinska Institute, SWEDEN
Abstract title:miRNAs role in sensitivity of lung adenocarcinomas to treatment
Rongbin Zhou, University of Science & Technology of China, CHINA
Abstract title:Targeting NLRP3 inflammasome to control inflammatory disorders

We encourage abstracts to contain new and unpublished materials. The abstracts must be submitted electronically by the abstract deadline. Selection of material for oral and poster presentation will be made by the organizers. Status (fellow's talk/poster) of abstracts will be posted on our web site as soon as decisions have been made by the organizers. 

We are eager to have as many young people as possible attend since they are likely to benefit most from this meeting. A certain number of presentations by graduate students and postdocs in this conference will be selected as fellowship (USD $100-$500) awards. For more details, please visit Stipends

We look forward to seeing you at Suzhou in November, 2015. 

Sponsored by:

Package Content:

Package Type

Early Registration

Late Registration

Payment Deadline:

October 12, 2015

Payment Deadline:

Before Arrival





















Please kindly note:

1. Registration includes food, but does NOT include Housing. Due to requests from participants to provide more housing at lower prices, we have expanded our housing options to include some lower priced nearby hotels. After completing the online registration, you will receive a link to the full list of housing options.
*Reference Room Rate:
CNY 500 per standard room per night in the Conference Hotel (Worldhotel Grand Dushulake Suzhou)
Up from CNY 200 per standard room per night in nearby budget hotels (within 5 km)
CNY 400-700 per standard room per night in nearby 4-5 star hotels

2. The meeting registration is an integral package. We encourage all our participants to stay for the full meeting period and communicate with each other. No refund/discount or day pass is available for partial participation.

3. The early price will be available if the full payment is finished before the exact due date.
For USD participants, we will automatically change your package price to the update one if we could not successfully charge the payment from your registered credit card before the deadline.
For CNY participants, we will automatically change your package price to the update one if our bank account could not receive your full payment by wire transfer before the deadline.

4. For late registrations, your registration materials may not be guaranteed since the order is usually made in advance.

5. Please inform us your special request on food (vegetarian, kosher…etc.) or other things during the online registration or email us as early as possible so that we could make relevant arrangement accordingly.

6. Student package is exclusively designed for all the graduate, undergraduate and doctor students who have not received the doctor degree. (Student ID will be required upon arrival).

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